Phospho-ATF2-T69/71 Rabbit Polyclonal Antibody (CABP0913)
- SKU:
- CABP0913
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | Phospho-ATF2-T69/71 Rabbit Polyclonal Antibody |
SKU: | CABP0913 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic phosphorylated peptide around T69 & T71 of human ATF2 (NP_001871.2?). |
Sequence: | QTPT P |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | HB16; CREB2; TREB7; CREB-2; CRE-BP1; Phospho-ATF2-T69/71 |
Positive Sample: | 293T |
Cellular Localization: | Cytoplasm, Mitochondrion outer membrane, Nucleus. |
Calculated MW: | 55kDa |
Observed MW: | 70kDa |
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene
Purification Method: | Affinity purification |
Gene ID: | 1386 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |