The Phospho-ARHGEF2 (S886) Polyclonal Antibody (CABP0926) is a valuable tool for researchers studying ARHGEF2, a protein involved in cell signaling and cytoskeletal rearrangement. This antibody, produced in rabbits, is highly specific to the phosphorylated form of ARHGEF2 at serine 886 and has been validated for use in Western blot applications.ARHGEF2, also known as Rho/Rac guanine nucleotide exchange factor 2, plays a crucial role in regulating cell migration, adhesion, and proliferation through activation of Rho GTPases. Phosphorylation at serine 886 has been shown to affect the activity of ARHGEF2 and its downstream signaling pathways. Research into the phosphorylation status of ARHGEF2 can provide insights into its function in various cellular processes and disease states.
With its high specificity and reactivity with human samples, the Phospho-ARHGEF2 (S886) Polyclonal Antibody is an essential tool for investigating the role of ARHGEF2 in signaling pathways associated with cancer, cardiovascular diseases, and other conditions. Its ability to detect phosphorylated ARHGEF2 in different cell types makes it an ideal choice for studies in cell biology and signaling research. Unlock the potential of ARHGEF2 phosphorylation with this reliable antibody for your research needs.
Product Name:
Phospho-ARHGEF2-S886 Rabbit Polyclonal Antibody
SKU:
CABP0926
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic phosphorylated peptide around S886 of human ARHGEF2 (NP_001155855.1?).
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
9181
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from C6 cells, using Phospho-ARHGEF2-S886 Rabbit pAb (CABP0926) at 1:1000 dilution.C6 were treated by CIP (20ul CIP for each 400ul cell lysate) at 37℃ for 1 hour.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
