Phospho-AMPKa1-T183/AMPKa2-T172 Polyclonal Antibody (CABP1283)
- SKU:
- CABP1283
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
Product Name: | Phospho-AMPKa1-T183/AMPKa2-T172 Polyclonal Antibody |
SKU: | CABP1283 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic phosphorylated peptide around T183 of human AMPKa1/AMPKa2PRKAA1 (NP_006242.5). |
Sequence: | LRTS C |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | AMPKa1/AMPKa2; Phospho-AMPKa1-T183/AMPKa2-T172 |
Positive Sample: | C2C12+oligomycin, C6+AICAR |
Conjugate: | Unconjugated |
Cellular Localization: | apical plasma membrane, cytoplasm, cytosol, nuclear speck, nucleoplasm, nucleus |
Calculated MW: | 64kDa/65kDa/62kDa |
Observed MW: | 62kDa |
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method: | Affinity purification |
Gene ID: | 5562/5563 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |