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Phospho-α-Synuclein-S129 Rabbit Polyclonal Antibody (CABP0450)

SKU:
CABP0450
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
$503
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Description

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Product Name:Phospho-α-Synuclein-S129 Rabbit Polyclonal Antibody
SKU:CABP0450
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic phosphorylated peptide around S129 of human alpha-Synuclein (NP_000336.1).
Sequence:MPSE E
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:PD1; NACP; PARK1; PARK4; Phospho-α-Synuclein-S129
Positive Sample:Mouse brain
Conjugate:Unconjugated
Cellular Localization:Cell junction, Cytoplasm, Membrane, Nucleus, Secreted, cytosol, synapse.
Calculated MW:14kDa
Observed MW:20kDa

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.

Purification Method:Affinity purification
Gene ID:6622
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from mouse brain tissue, using Phospho-α-Synuclein-S129 Rabbit pAb (CABP0450).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.

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