Description
Product Name: | Phospho-AKT2 specific-S474 Polyclonal Antibody |
SKU: | CABP1403 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic phosphorylated peptide around S474 of human AKT2 specific . |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA; Phospho-AKT2 specific-S474 |
Positive Sample: | 293F treated by Calyculin A,293F treated by Calyculin A after transfected with AKT2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Early endosome, Nucleus, Peripheral membrane protein. |
Calculated MW: | 56kDa |
Observed MW: | 63kDa/90kDa |
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The gene serves as an oncogene in the tumorigenesis of cancer cells For example, its overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins, and has also been implicated in insulin signaling.
Purification Method: | Affinity purification |
Gene ID: | 208 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |