The Phospho-ADD1/ADD2 (S726/713) Antibody (PACO00316) is a valuable tool for researchers studying the phosphorylation of ADD1 and ADD2 proteins, which play a key role in cell adhesion and cytoskeletal organization. This polyclonal antibody, raised in rabbits, is highly specific and reacts with phosphorylated forms of the ADD1 and ADD2 proteins in human samples. Validated for use in Western blot applications, this antibody allows for the detection and analysis of phosphorylated ADD1 and ADD2 in various cell types.ADD1 and ADD2 proteins are crucial for the maintenance of cell structure and function, and their phosphorylation status can impact cell adhesion and migration processes.
Understanding the phosphorylation of ADD1 and ADD2 is important for research into cell biology, cancer metastasis, and other cellular processes where cytoskeletal dynamics play a role. The Phospho-ADD1/ADD2 (S726/713) Antibody provides researchers with a powerful tool to investigate the role of phosphorylation in these processes and advance knowledge in the field of cellular biology.
Antibody Name:
Phospho-ADD1/ADD2 (S726/713) Antibody
Antibody SKU:
PACO00316
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC, IF
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from human Adducin alpha/Beta around the phosphorylation site of S726/713.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.
NCBI Summary:
Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017]
