Phospho-Acetyl CoA Carboxylase-S79 Polyclonal Antibody (CABP1410)
The Phospho-Acetyl-CoA Carboxylase (S79) Polyclonal Antibody is a valuable tool for researchers studying the phosphorylation status of Acetyl-CoA Carboxylase (ACC) at serine 79. ACC is a key enzyme involved in fatty acid metabolism, and its phosphorylation at S79 regulates its activity, impacting lipid synthesis and energy metabolism.This rabbit-raised antibody is highly specific to the phosphorylated form of ACC at S79 in human samples, making it ideal for Western blot applications. By detecting and quantifying the phosphorylation of ACC at S79, researchers can gain insights into lipid metabolism, insulin signaling, and potential therapeutic targets for metabolic disorders such as obesity and diabetes.
The Phospho-Acetyl-CoA Carboxylase (S79) Polyclonal Antibody is a valuable tool for studies in metabolic research, lipid metabolism, and the development of novel therapeutic strategies for metabolic diseases. Its specificity and reliability make it a trusted reagent for investigating the role of ACC phosphorylation in health and disease.
Product Name:
Phospho-Acetyl CoA Carboxylase-S79 Polyclonal Antibody
SKU:
CABP1410
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic phosphorylated peptide around S79 of human Acetyl CoA Carboxylase.
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
31/32
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of NIH/3T3, using Phospho-Acetyl CoA Carboxylase-S79 Rabbit PAb (CABP1410) at 1:1000 dilution.NIH/3T3 cells were treated by oligomycin (0.5 uM) at 37℃ for 30 minutes.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
