Phospho-Acetyl CoA Carboxylase-S79 Monoclonal Antibody (CABP1388)
The Phospho Acetyl-CoA Carboxylase (S79) Monoclonal Antibody is a valuable tool for researchers studying the phosphorylation of Acetyl-CoA carboxylase at Serine 79, a crucial post-translational modification involved in lipid metabolism regulation. This antibody, produced using monoclonal techniques, exhibits high specificity and sensitivity for detecting phosphorylated Acetyl-CoA carboxylase at Serine 79 in human samples.This antibody is well-suited for Western blot applications, allowing for precise and accurate analysis of Acetyl-CoA carboxylase phosphorylation in various cell types and tissues.
By targeting the phosphorylated form of Acetyl-CoA carboxylase, researchers can gain insights into its role in metabolic pathways and its potential implications in diseases such as obesity, diabetes, and cancer.Overall, the Phospho Acetyl-CoA Carboxylase (S79) Monoclonal Antibody offers a reliable and versatile tool for investigating the regulation of lipid metabolism through the phosphorylation of Acetyl-CoA carboxylase at Serine 79, making it a valuable asset for studies in molecular biology, biochemistry, and metabolic research.
Product Name:
Phospho-Acetyl CoA Carboxylase-S79 Monoclonal Antibody
SKU:
CABP1388
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic phosphorylated peptide around S79 of human Acetyl CoA Carboxylase.
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
31/32
Clone Number:
ARC56611
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of NIH/3T3, using Phospho-Acetyl CoA Carboxylase-S79 antibody (CABP1388) at 1:7000 dilution.NIH/3T3 cells were treated by oligomycin (0.5 uM) at 37℃ for 30 minutes.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
