The Phosducin Polyclonal Antibody (CAB8447) is a valuable tool for researchers studying the protein Phosducin, which plays a crucial role in signal transduction pathways in various cell types. This polyclonal antibody is raised in rabbits and is highly reactive with human samples, making it an ideal choice for experiments involving Phosducin in Western blot applications.Phosducin is known for its involvement in regulating G protein signaling and neurotransmitter release, making it a key player in processes related to neuronal function and communication. By targeting the Phosducin protein, researchers can gain valuable insights into its function and contribution to cellular signaling pathways.
This antibody's specificity and sensitivity make it a reliable option for studies in neuroscience, cell biology, and pharmacology, offering researchers the opportunity to explore the role of Phosducin in various physiological and pathological conditions. With its potential applications in drug development and therapeutic interventions, the Phosducin Polyclonal Antibody (CAB8447) is a valuable asset for scientific investigations aimed at understanding signal transduction mechanisms.
Product Name:
PDC Rabbit Polyclonal Antibody
SKU:
CAB8447
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human PDC (NP_002588.3).
This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
5132
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PDC Rabbit pAb (CAB8447) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
