PHLPP1 Rabbit Polyclonal Antibody (CAB9542)
- SKU:
- CAB9542
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- IF
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | PHLPP1 Rabbit Polyclonal Antibody |
SKU: | CAB9542 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1160-1428 of human PHLPP1 (NP_919431.2). |
Sequence: | DQPS TGDA SGAP AVWS HGYT EASG VKNK LCVA ALSV NNFC DNRE ALYG VFDG DRNV EVPY LLQC TMSD ILAE ELQK TKNE EEYM VNTF IVMQ RKLG TAGQ KLGG AAVL CHIK HDPV DPGG SFTL TSAN VGKC QTVL CRNG KPLP LSRS YIMS CEEE LKRI KQHK AIIT EDGK VNGV TEST RILG YTFL HPSV VPRP HVQS VLLT PQDE FFIL GSKG LWDS LSVE EAVE AVRN VPDA LAAA KKLC TLAQ SYGC HDSI SAVV VQLS VTED S |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | SCOP; PHLPP; PPM3A; PLEKHE1; PHLPP1 |
Positive Sample: | HeLa,SH-SY5Y,Mouse testis,Mouse brain,Rat testis,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Membrane, Nucleus, Peripheral membrane protein. |
Calculated MW: | 185kDa |
Observed MW: | 185kDa |
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.
Purification Method: | Affinity purification |
Gene ID: | 23239 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |