The PHLDA2 Polyclonal Antibody (CAB6244) is a valuable tool for research involving PHLDA2, a protein involved in cell growth regulation and apoptosis. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the PHLDA2 protein, this antibody enables researchers to detect and analyze PHLDA2 expression in various cell types, making it an essential component for studies in cancer biology and cell signaling pathways.PHLDA2, also known as T-cell death-associated gene 51 (TDAG51), is a crucial regulator of cell growth and survival, with implications in cancer development and progression.
Its role in apoptosis and cell cycle regulation makes it a promising target for therapeutic interventions targeting cancer cells. By studying the function of PHLDA2, researchers can gain insights into the mechanisms underlying tumor growth and potentially identify new strategies for cancer treatment.Overall, the PHLDA2 Polyclonal Antibody (CAB6244) is a reliable tool for investigating the role of PHLDA2 in cancer biology and cell signaling pathways. Its high specificity and sensitivity make it an essential reagent for researchers interested in understanding the molecular mechanisms of cancer progression and identifying potential targets for anti-cancer therapies.
Product Name:
PHLDA2 Rabbit Polyclonal Antibody
SKU:
CAB6244
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human PHLDA2 (NP_003302.1).
This gene is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver.
Purification Method:
Affinity purification
Gene ID:
7262
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from PC-3 cells using PHLDA2 Rabbit pAb(CAB6244) at 1:4000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime:180s.
