The PHLDA1 Polyclonal Antibody (PAC011219) is a valuable tool for research involving PHLDA1, a protein implicated in cell death and proliferation signaling pathways. This antibody, raised in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples. By binding to the PHLDA1 protein, this antibody enables researchers to detect and analyze PHLDA1 expression in various cell types, making it a valuable tool for studies in cell biology and cancer research.PHLDA1, also known as T-cell death-associated gene 51, is involved in regulating cell growth and apoptosis, making it a key player in the development and progression of cancer.
Understanding the role of PHLDA1 in cellular processes is essential for advancing research into cancer therapies and identifying potential targets for intervention. The PHLDA1 Polyclonal Antibody provides researchers with a reliable tool for investigating the function of PHLDA1 in cellular pathways, opening up new possibilities for therapeutic development.
pleckstrin homology-like domain, family A, member 1;PHLDA1;DT1P1B11;MGC131738;PHRIP;TDAG51 ;
UniProt Protein Function:
PHLDA1: Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.Protein type: Nucleolus; ApoptosisChromosomal Location of Human Ortholog: 12q15Cellular Component: cytosolMolecular Function: protein bindingBiological Process: G2/M transition of mitotic cell cycle
UniProt Protein Details:
NCBI Summary:
This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1. [provided by RefSeq, Jul 2008]