The PHIP Polyclonal Antibody (CAB7207) is a valuable tool for researchers studying the PHIP protein, which plays a crucial role in cellular metabolism and energy homeostasis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the PHIP protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for investigations in the fields of metabolism, obesity, and diabetes research.PHIP, also known as pleckstrin homology domain-interacting protein, is involved in regulating insulin signaling and glucose metabolism, making it a key player in metabolic disorders and related conditions.
Understanding the functions and mechanisms of PHIP is essential for developing targeted therapies for metabolic diseases and improving overall health outcomes. Research using the PHIP Polyclonal Antibody can provide valuable insights into the role of PHIP in various physiological processes and diseases, paving the way for innovative treatment strategies in the future.
Product Name:
PHIP Rabbit Polyclonal Antibody
SKU:
CAB7207
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1542-1821 of human PHIP (NP_060404.3).
This gene encodes a protein that binds to the insulin receptor substrate 1 protein and regulates glucose transporter translocation in skeletal muscle cells. The encoded protein may also regulate growth and survival of pancreatic beta cells. Elevated copy number of this gene may be associated with melanoma severity and the encoded protein may promote melanoma metastasis in human patients.
Purification Method:
Affinity purification
Gene ID:
55023
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PHIP Rabbit pAb (CAB7207) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
