PHGDH Rabbit Polyclonal Antibody (CAB10461)
- SKU:
- CAB10461
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PHGDH Rabbit Polyclonal Antibody |
SKU: | CAB10461 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 264-533 of human PHGDH (NP_006614.2). |
Sequence: | EEPP RDRA LVDH ENVI SCPH LGAS TKEA QSRC GEEI AVQF VDMV KGKS LTGV VNAQ ALTS AFSP HTKP WIGL AEAL GTLM RAWA GSPK GTIQ VITQ GTSL KNAG NCLS PAVI VGLL KEAS KQAD VNLV NAKL LVKE AGLN VTTS HSPA APGE QGFG ECLL AVAL AGAP YQAV GLVQ GTTP VLQG LNGA VFRP EVPL RRDL PLLL FRTQ TSDP AMLP TMIG LLAE AGVR LLSY QTSL VSDG ETWH VMGI SSLL PSLE AWKQ HVTE AFQF HF |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:100 - 1:500 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | NLS; PDG; PGD; NLS1; PGAD; PGDH; SERA; 3PGDH; 3-PGDH; PHGDHD; HEL-S-113; PHGDH |
Positive Sample: | HeLa,HT-29,MCF7,NIH/3T3,C6,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, extracellular exosome |
Calculated MW: | 57kDa |
Observed MW: | 57kDa |
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.
Purification Method: | Affinity purification |
Gene ID: | 26227 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |