The PHF21A Polyclonal Antibody (CAB6330) is a valuable tool for researchers studying the PHF21A protein, which is involved in chromatin remodeling and gene transcription regulation. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for Western blot applications. By binding to PHF21A, researchers can accurately detect and analyze this protein in various cell types, providing insight into its role in molecular mechanisms related to cancer, gene expression, and epigenetic regulation.PHF21A, also known as PHD finger protein 21A, is a key player in chromatin structure organization and transcriptional regulation.
Dysregulation of PHF21A has been implicated in various diseases, including cancer and neurodevelopmental disorders. Therefore, understanding the functions and interactions of PHF21A is essential for developing targeted therapies and diagnostic tools for these conditions.By utilizing the PHF21A Polyclonal Antibody (CAB6330), researchers can delve deeper into the intricate mechanisms involving PHF21A, paving the way for advancements in molecular biology, disease research, and therapeutic interventions.
Product Name:
PHF21A Rabbit Polyclonal Antibody
SKU:
CAB6330
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 461-680 of human PHF21A (NP_001095272.1).
The PHF21A gene encodes BHC80, a component of a BRAF35 (MIM 605535)/histone deacetylase (HDAC; see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS) (Hakimi et al., 2002 [PubMed 12032298]).
Purification Method:
Affinity purification
Gene ID:
51317
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Mouse liver, using PHF21A Rabbit pAb (CAB6330) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
