The PHF19 Polyclonal Antibody (CAB8065) is a valuable tool for researchers studying PHF19, a protein involved in epigenetic regulation and gene expression. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to PHF19, this antibody enables precise detection and analysis of the protein in a variety of cell types, making it ideal for studies in epigenetics, gene regulation, and cancer research.
PHF19, also known as a component of the Polycomb repressive complex 2 (PRC2), plays a crucial role in maintaining chromatin structure and regulating gene transcription. Dysregulation of PHF19 has been associated with various diseases, including cancer and developmental disorders. Understanding the function of PHF19 is essential for uncovering its role in disease development and for designing targeted therapies that modulate gene expression for therapeutic purposes.
Product Name:
PHF19 Rabbit Polyclonal Antibody
SKU:
CAB8065
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 of human PHF19 (NP_001009936.1).
Enables methylated histone binding activity. Involved in positive regulation of histone H3-K27 methylation. Colocalizes with ESC/E(Z) complex.
Purification Method:
Affinity purification
Gene ID:
26147
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PHF19 Rabbit pAb (CAB8065) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
