The PHF11 Polyclonal Antibody (CAB7803) is a valuable tool for researchers studying PHF11, a protein involved in chromatin regulation and gene expression. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blotting applications. It specifically binds to the PHF11 protein, allowing for its detection and analysis in a variety of cell types.PHF11, a member of the PHD finger family of proteins, has been linked to various biological processes including transcriptional regulation, cell differentiation, and cellular proliferation.
Its role in chromatin remodeling makes it a key player in epigenetic regulation, with implications for diseases such as cancer and neurodevelopmental disorders. By investigating the function of PHF11, researchers can gain insights into its contribution to these conditions and potentially identify novel therapeutic targets.
Product Name:
PHF11 Rabbit Polyclonal Antibody
SKU:
CAB7803
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human PHF11 (NP_001035533.1).
This gene encodes a protein containing a PHD (plant homeodomain) type zinc finger. This gene has been identified in some studies as a candidate gene for asthma. Naturally-occurring readthrough transcription may occur from the upstream SETDB2 (SET domain bifurcated 2) gene to this locus. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
51131
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PHF11 Rabbit pAb (CAB7803) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
