PHF1 Rabbit Polyclonal Antibody (CAB8450)
- SKU:
- CAB8450
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PHF1 Rabbit Polyclonal Antibody |
SKU: | CAB8450 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PHF1 (NP_077084.1). |
Sequence: | MAQP PRLS RSGA SSLW DPAS PAPT SGPR PRLW EGQD VLAR WTDG LLYL GTIK KVDS AREV CLVQ FEDD SQFL VLWK DISP AALP GEEL LCCV CRSE TVVP GNRL VSCE KCRH AYHQ DCHV PRAP APGE GEGT SWVC RQCV FAIA TKRG GALK KGPY ARAM LGMK LSLP YGLK GLDW DAGH LSNR QQSY CYCG GPGE WNLK MLQC RSCL QWFH EACT QCLS KPLL YGDR FYEF ECCV CRGG PEKV RRLQ LRWV DVAH LVLY |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PCL1; PHF2; hPHF1; MTF2L2; TDRD19C; PHF1 |
Positive Sample: | A-549,HeLa,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 62kDa |
Observed MW: | 68kDa |
This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5252 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |