Prolyl hydroxylase PHD1 (EGLN2) Rabbit Monoclonal Antibody (CAB3730)
- SKU:
- CAB3730
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Prolyl hydroxylase PHD1 (EGLN2) Rabbit Monoclonal Antibody |
SKU: | CAB3730 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Prolyl hydroxylase PHD1 (EGLN2) (Q96KS0). |
Sequence: | MDSP CQPQ PLSQ ALPQ LPGS SSEP LEPE PGRA RMGV ESYL PCPL LPSY HCPG VPSE ASAG SGTP RATA TSTT ASPL RDGF GGQD GGEL RPLQ SEGA AALV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | EIT6; PHD1; EIT-6; HPH-1; HPH-3; HIFPH1; HIF-PH1; Prolyl hydroxylase PHD1 (EGLN2) |
Positive Sample: | A-549,MCF7,PC-3,Mouse lung,Mouse testis,Mouse brain,Rat testis,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 44kDa |
Observed MW: | 44kDa |
The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.
Purification Method: | Affinity purification |
Gene ID: | 112398 |
Clone Number: | ARC0230 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |