PHC2 Rabbit Polyclonal Antibody (CAB14727)
- SKU:
- CAB14727
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PHC2 Rabbit Polyclonal Antibody |
SKU: | CAB14727 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PHC2 (NP_004418.2). |
Sequence: | MTSG NGNS ASSI AGTA PQNG ENKP PQAI VKPQ ILTH VIEG FVIQ EGAE PFPV GRSS LLVG NLKK KYAQ GFLP EKLP QQDH TTTT DSEM EEPY LQES KEEG APLK LKCE LCGR VDFA YKFK RSKR FCSM ACAK RYNV GCTK RVGL FHSD RSKL QKAG AATH NRRR ASKA SLPP LTKD TKKQ PTGT VPLS VTAA LQLT HSQE DSSR CSDN SSYE EPLS PISA SSST SRRR QGQR DLEL PDMH |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PH2; EDR2; HPH2; PHC2 |
Positive Sample: | HT-29,HeLa,MCF7,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 91kDa |
Observed MW: | 37kDa |
In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1912 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |