The PHC2 Polyclonal Antibody (CAB14610) is a valuable tool for researchers studying PHC2, a key protein involved in gene regulation and cell differentiation. This antibody, generated in rabbits, shows high reactivity with human samples and is suitable for use in Western blot applications. By binding specifically to PHC2, researchers can detect and analyze the protein in various cell types, making it an essential tool for studies in developmental biology and cancer research.PHC2, also known as Polyhomeotic-like protein 2, plays a crucial role in regulating gene expression and controlling cell fate during development.
Its involvement in epigenetic regulation and chromatin organization makes it an attractive target for understanding processes like stem cell differentiation and tumor formation. Research into PHC2 can provide valuable insights into mechanisms underlying developmental disorders and cancer progression, leading to potential therapeutic interventions targeting this protein.Overall, the PHC2 Polyclonal Antibody (CAB14610) is a reliable tool for investigating the role of PHC2 in various biological processes, offering researchers a means to explore its function and potential implications in disease pathology.
Product Name:
PHC2 Rabbit Polyclonal Antibody
SKU:
CAB14610
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 250-323 of human PHC2 (NP_004418.2).
In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1912
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PHC2 Rabbit pAb (CAB14610) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
