PHC2 Rabbit Polyclonal Antibody (CAB14610)
- SKU:
- CAB14610
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
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Description
Product Name: | PHC2 Rabbit Polyclonal Antibody |
SKU: | CAB14610 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-323 of human PHC2 (NP_004418.2). |
Sequence: | HFLP SEPT KWNV EDVY EFIR SLPG CQEI AEEF RAQE IDGQ ALLL LKED HLMS AMNI KLGP ALKI YARI SMLK DS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PH2; EDR2; HPH2; PHC2 |
Positive Sample: | DU145,HT-29,HeLa,Jurkat,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 91kDa |
Observed MW: | 45kDa |
In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1912 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |