The Phactr4 Monoclonal Antibody (PACO11205) is a vital tool for researchers studying Phactr4, a protein known for its involvement in cellular processes such as cell proliferation and migration. This antibody, produced through hybridoma technology, exhibits high specificity for Phactr4 and is suitable for various experimental techniques, including immunofluorescence and immunohistochemistry.Phactr4, a member of the phosphatase and actin regulator family, plays a crucial role in regulating cell morphology and cytoskeletal dynamics.
It is associated with cellular signaling pathways that govern cell growth and survival, making it a target of interest in cancer research and developmental biology. The Phactr4 antibody enables precise detection and visualization of Phactr4 expression in cell lines and tissue samples, facilitating detailed analysis and furthering our understanding of its biological functions.
phosphatase and actin regulator 4;PHACTR4;DKFZp686L07205;FLJ13171;MGC20618;MGC34186 ;
UniProt Protein Function:
PHACTR4: a protein of unknown function. Contains three RPEL repeats named after four conserved amino acids it contains. Protein type: Phosphatase; Actin-bindingChromosomal Location of Human Ortholog: 1p35.3Cellular Component: lamellipodiumMolecular Function: actin binding; protein phosphatase 1 bindingBiological Process: actin cytoskeleton organization and biogenesis; enteric nervous system development; neural crest cell migration; neural tube closure; positive regulation of catalytic activity; regulation of cell cycle; Rho protein signal transduction
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
