The PGP9.5 Rabbit Monoclonal Antibody (CAB19101) is ideal for researchers studying PGP9.5, a marker for neurons and neuroendocrine cells. This antibody, developed using rabbit monoclonal technology, shows high reactivity with human samples and is validated for use in various applications, including immunohistochemistry and ELISA.PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase L1 (UCHL1), is a widely used neuronal marker due to its abundance in neurons and neuroendocrine cells.
The protein plays essential roles in neuronal function and is implicated in neurodegenerative diseases, making it a valuable target for neurological research.This antibody specifically binds to PGP9.5 protein, allowing for precise detection and localization in tissue samples. Its sensitivity and specificity make it a valuable tool for studying neuronal populations, neurodegenerative diseases, and neuroendocrine disorders, providing insights into the pathophysiology of these conditions.
Product Name:
PGP9.5/UCHL1 Rabbit Monoclonal Antibody
SKU:
CAB19101
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human PGP9.5/UCHL1 (NP_004172.2).
The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.
Purification Method:
Affinity purification
Gene ID:
7345
Clone Number:
ARC50371
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PGP9.5/UCHL1 Rabbit mAb (CAB19101) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
