The PGM2L1 Polyclonal Antibody (PAC037150) is a valuable tool for researchers studying PGM2L1, a protein involved in various cellular functions, including metabolism and energy production. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the PGM2L1 protein, this antibody enables detection and analysis in a variety of cell types, making it a versatile option for studies in metabolic regulation, cancer biology, and other related fields.
PGM2L1, also known as phosphoglucomutase-like 1, plays a crucial role in glucose metabolism and glycosylation processes within cells. Dysregulation of PGM2L1 has been implicated in diseases such as cancer, diabetes, and metabolic disorders, highlighting its potential as a therapeutic target. By investigating the function and expression of PGM2L1, researchers can gain insights into cellular pathways and mechanisms that may be exploited for the development of novel treatments and interventions.
Western blot. All lanes: PGM2L1 antibody at 0.8µg/ml. Lane 1: HL60 whole cell lysate. Lane 2: MCF-7 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 71 kDa. Observed band size: 71 kDa.
Immunohistochemistry of paraffin-embedded human glioma using PACO37150 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human cervical cancer using PACO37150 at dilution of 1:100.
Background:
Glucose 1,6-bisphosphate synthase using 1,3-bisphosphoglycerate as a phosphate donor and a series of 1-phosphate sugars as acceptors, including glucose 1-phosphate, mannose 1-phosphate, ribose 1-phosphate and deoxyribose 1-phosphate. 5 or 6-phosphosugars are bad substrates, with the exception of glucose 6-phosphate. Also synthesizes ribose 1,5-bisphosphate. Has only low phosphopentomutase and phosphoglucomutase activities.
PGM2L1: Glucose 1,6-bisphosphate synthase using 1,3- bisphosphoglycerate as a phosphate donor and a series of 1- phosphate sugars as acceptors, including glucose 1-phosphate, mannose 1-phosphate, ribose 1-phosphate and deoxyribose 1- phosphate. 5 or 6-phosphosugars are bad substrates, with the exception of glucose 6-phosphate. Also synthesizes ribose 1,5- bisphosphate. Has only low phosphopentomutase and phosphoglucomutase activities. Belongs to the phosphohexose mutase family.Protein type: Carbohydrate Metabolism - starch and sucrose; EC 2.7.1.106; IsomeraseChromosomal Location of Human Ortholog: 11q13.4Cellular Component: cytosolMolecular Function: glucose-1,6-bisphosphate synthase activity