The PGM2L1 Polyclonal Antibody (PACO11201) is a valuable tool for researchers studying PGM2L1, a key enzyme involved in carbohydrate metabolism. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the PGM2L1 protein, this antibody allows for precise detection and analysis of PGM2L1 in a variety of cell types, making it ideal for studies in biochemistry and metabolic disease research.
PGM2L1 is a crucial enzyme in the glycolysis pathway, playing a vital role in the conversion of glucose to energy. Dysregulation of PGM2L1 has been associated with metabolic disorders such as diabetes and obesity, making it a promising target for therapeutic interventions. Understanding the function and regulation of PGM2L1 is essential for developing strategies to combat metabolic diseases and improve overall health outcomes.
PGM2L1: Glucose 1,6-bisphosphate synthase using 1,3- bisphosphoglycerate as a phosphate donor and a series of 1- phosphate sugars as acceptors, including glucose 1-phosphate, mannose 1-phosphate, ribose 1-phosphate and deoxyribose 1- phosphate. 5 or 6-phosphosugars are bad substrates, with the exception of glucose 6-phosphate. Also synthesizes ribose 1,5- bisphosphate. Has only low phosphopentomutase and phosphoglucomutase activities. Belongs to the phosphohexose mutase family.Protein type: Carbohydrate Metabolism - starch and sucrose; EC 2.7.1.106; IsomeraseChromosomal Location of Human Ortholog: 11q13.4Cellular Component: cytosolMolecular Function: glucose-1,6-bisphosphate synthase activity
