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PGM1 Polyclonal Antibody

SKU:
CAB21540
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€129 - €359
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Description

Product Name:PGM1 Polyclonal Antibody
Product Code:CAB21540
Reactivity:Human
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location:Cytoplasm

The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PGM1 (NP_002624.2).
Sequence:MVKIV TVKTQ AYQDQ KPGTS GLRKR VKVFQ SSANY AENFI QSIIS TVEPA QRQEA TLVVG GDGRF YMKEA IQLIA RIAAA NGIGR LVIGQ NGILS TPAVS CIIRK IKAIG GIILT ASHNP GGPNG DFGIK FNISN GGPAP EAITD KIFQI SKTIE EYAVC PDLKV DLGVL GKQQF DLENK FKPFT VEIVD SVEAY ATMLR SIFDF SALKE LLSGP NRLKI RIDAM HGVVG PYVKK ILCEE LGAPA NSAVN CVPLE DFGGH HPDPN LTYAA DLVET MKSGE HDFGA AFDGD GDRNM ILGKH
Synonyms:CDG1T, GSD14
Calculated MW:61kDa
Observed MW:Refer to figures

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