PGLYRP3 Antibody (PACO58841)
- SKU:
- PACO58841
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
PGLYRP3 Antibody (PACO58841)
The PGLYRP3 Polyclonal Antibody (PAC058841) is a valuable tool for researchers studying PGLYRP3, a protein involved in innate immunity and inflammatory responses. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blotting.PGLYRP3, also known as N-acetylmuramoyl-L-alanine amidase, plays a critical role in sensing and responding to bacterial infections by breaking down bacterial cell wall components.
It is involved in the immune response to pathogens and has been implicated in conditions such as sepsis and inflammatory bowel disease.By targeting PGLYRP3 with this antibody, researchers can investigate its role in immune defense mechanisms and inflammatory pathways. Understanding the function of PGLYRP3 may provide insights into potential therapeutic targets for infectious and inflammatory diseases.
| Antibody Name: | PGLYRP3 Antibody (PACO58841) |
| Antibody SKU: | PACO58841 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Peptidoglycan recognition protein 3 protein (90-222AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: MCF-7 whole cell lysate, Colo320 whole cell lysate. All lanes: PGLYRP3 antibody at 4.86µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 38 kDa. Observed band size: 38 kDa. |
| Background: | Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity. |
| Synonyms: | Peptidoglycan recognition protein 3 (Peptidoglycan recognition protein I-alpha) (PGLYRPIalpha) (PGRP-I-alpha) (Peptidoglycan recognition protein intermediate alpha), PGLYRP3, PGRPIA |
| UniProt Protein Function: | PGLYRP3: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 1q21Molecular Function: peptidoglycan binding; peptidoglycan receptor activityBiological Process: defense response to Gram-positive bacterium; detection of bacterium |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014] |
| UniProt Code: | Q96LB9 |
| NCBI GenInfo Identifier: | 16418405 |
| NCBI Gene ID: | |
| NCBI Accession: | NP_443123.1 |
| UniProt Secondary Accession: | Q96LB9,Q5SY65, A1A4U8 |
| UniProt Related Accession: | Q96LB9 |
| Molecular Weight: | |
| NCBI Full Name: | |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Peptidoglycan recognition protein 3 |
| UniProt Synonym Protein Names: | Peptidoglycan recognition protein I-alpha; PGLYRPIalpha; PGRP-I-alpha; Peptidoglycan recognition protein intermediate alpha |
| Protein Family: | |
| UniProt Gene Name: | PGLYRP3Â Â |
| UniProt Entry Name: | PGRP3_HUMAN |
| Antibodies | ELISA Kits |
| PGLYRP3 Antibody (PACO11198) | Human Peptidoglycan recognition protein 3 (PGLYRP3) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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