The PGlyRP3 Polyclonal Antibody (PAC011198) is a valuable tool for researchers studying pGlyRP3, a protein involved in innate immunity and inflammatory responses. This antibody, raised in rabbits, has high reactivity with human samples and is validated for use in a variety of applications, including Western blotting.pGlyRP3, also known as peptidoglycan recognition protein 3, plays a crucial role in detecting and responding to bacterial infections. Its ability to bind to bacterial cell wall components helps to activate the immune response and initiate inflammation.
This makes pGlyRP3 an important target for research in infectious diseases and immunology.By using the PAC011198 antibody, researchers can detect and analyze pGlyRP3 in different cell types, providing valuable insights into its function and potential therapeutic implications. Understanding the role of pGlyRP3 in immune responses can lead to the development of new treatments for bacterial infections and inflammatory conditions.
peptidoglycan recognition protein 3;PGLYRP3;MGC149197;PGRP-Ialpha;PGRPIA ;
UniProt Protein Function:
PGLYRP3: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 1q21Molecular Function: peptidoglycan binding; peptidoglycan receptor activityBiological Process: defense response to Gram-positive bacterium; detection of bacterium
UniProt Protein Details:
NCBI Summary:
This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014]
