The PGLS Polyclonal Antibody (CAB8366) is a valuable tool for researchers studying PGLS, a key enzyme involved in the regulation of purine metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the PGLS protein, this antibody enables the detection and analysis of PGLS in various cell types, making it ideal for investigations in biochemistry and metabolic research.PGLS plays a crucial role in the metabolic pathway that converts 6-phosphogluconolactone to 6-phosphogluconate, which is essential for maintaining cellular energy balance.
Dysregulation of PGLS activity has been linked to various metabolic disorders, making it a potential target for therapeutic interventions. Studying the function of PGLS can provide valuable insights into metabolic processes and may lead to the development of novel treatments for metabolic disorders and diseases related to purine metabolism.
Product Name:
PGLS Rabbit Polyclonal Antibody
SKU:
CAB8366
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-258 of human PGLS (NP_036220.1).
Enables 6-phosphogluconolactonase activity. Involved in pentose-phosphate shunt. Located in extracellular exosome.
Purification Method:
Affinity purification
Gene ID:
25796
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PGLS Rabbit pAb (CAB8366) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
