PGD Monoclonal Antibody [PAT46B3AT] (CPAB0239)
- SKU:
- CPAB0239
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT46B3AT
- Applications:
- WB
- ELISA
- FC
Description
PGD Monoclonal Antibody [PAT46B3AT] (CPAB0239)
The PGD Polyclonal Antibody (CPAB0239) is a valuable tool for researchers studying the enzyme prostaglandin D2 synthase (PGD), which plays a crucial role in the production of prostaglandins involved in inflammation and allergic reactions. This antibody, raised in rabbits, is highly specific to human samples and is validated for use in various applications, including Western blotting.PGD is implicated in a variety of conditions, including asthma, allergic rhinitis, and inflammatory diseases.
By targeting PGD with this antibody, researchers can gain deeper insights into the mechanisms underlying these conditions and develop potential therapeutic strategies. With its high reactivity and specificity, the PGD Polyclonal Antibody is an essential tool for studies in immunology, allergy research, and drug development.
Product Name: | PGD Antibody |
Product Sku: | CPAB0239 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human PGD mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PGD amino acids 1-483 purified from Ecoli. |
Clone: | PAT46B3AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA, Flow Cytometry |
Purification Method: | PGD antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG1 |
Background: | 6PGD is the second dehydrogenase in the pentose phosphate shunt. Pentose is neccesary for nucleic acid biosynthesis. The pentose phosphate cycle is a major source of NADPH 6PGD deficiency is usually asymptomatic, and the inheritance of this disorder is autosomal dominant. PGD deficiency raises the erythrocyte pyruvate kinase levels of activity and decreases glutathione synthetase, resulting in hemolysis. |
Synonyms: | EC 1.1.1.44, 6PGD, PGDH, 6-phosphogluconate dehydrogenase decarboxylating, PGD. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |