PGBD5 Antibody (PACO18489)
- SKU:
- PACO18489
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
PGBD5 Antibody (PACO18489)
The PGD5 Polyclonal Antibody (PAC018489) is a valuable tool for researchers studying PGD5, an enzyme involved in the biosynthesis of prostaglandin D2. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PGD5 protein, this antibody enables researchers to detect and analyze PGD5 expression in various cell types, making it ideal for studies in inflammation, allergies, and lipid metabolism.
PGD5 is known for its role in mediating inflammatory responses and allergic reactions through the generation of prostaglandin D2, a potent lipid mediator. Understanding the function of PGD5 is essential for uncovering its involvement in diseases such as asthma, allergic rhinitis, and inflammatory disorders. By targeting PGD5, researchers may uncover new therapeutic strategies for managing these conditions and modulating inflammatory pathways.
| Antibody Name: | PGBD5 Antibody (PACO18489) |
| Antibody SKU: | PACO18489 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human PGBD5 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18489(PGBD5 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO18489(PGBD5 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. |
| Synonyms: | piggyBac transposable element derived 5 |
| UniProt Protein Function: | Subcellular location: Membrane; Single-pass membrane protein Potential. Sequence caution: The sequence CAI13996.2 differs from that shown. Reason: Erroneous gene model prediction. |
| UniProt Protein Details: | |
| NCBI Summary: | The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. [provided by RefSeq, May 2010] |
| UniProt Code: | Q8N414 |
| NCBI GenInfo Identifier: | 385198065 |
| NCBI Gene ID: | 79605 |
| NCBI Accession: | NP_001245240.1 |
| UniProt Secondary Accession: | Q8N414,Q5SR37, Q6PJN2, A0PJF3, B9EK58 |
| UniProt Related Accession: | Q8N414 |
| Molecular Weight: | |
| NCBI Full Name: | piggyBac transposable element-derived protein 5 |
| NCBI Synonym Full Names: | piggyBac transposable element derived 5 |
| NCBI Official Symbol: | PGBD5 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | piggyBac transposable element-derived protein 5 |
| UniProt Protein Name: | PiggyBac transposable element-derived protein 5 |
| UniProt Synonym Protein Names: | |
| Protein Family: | PiggyBac transposable element-derived protein |
| UniProt Gene Name: | PGBD5 |
| UniProt Entry Name: | PGBD5_HUMAN |
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