The PGAM1 Rabbit Monoclonal Antibody (CAB4170) is a highly specific antibody designed for research involving PGAM1, a key enzyme involved in glycolysis. The antibody, generated in rabbits, exhibits strong reactivity with human samples and is validated for use in various applications including Western blot, immunohistochemistry, and immunofluorescence.PGAM1 is a phosphoglycerate mutase enzyme that plays a crucial role in glycolysis by catalyzing the conversion of 3-phosphoglycerate to 2-phosphoglycerate. Dysregulation of PGAM1 expression has been linked to various diseases including cancer, metabolic disorders, and neurodegenerative diseases.
The PGAM1 antibody allows for the detection and analysis of PGAM1 protein levels in different cell types, making it an essential tool for researchers studying metabolic pathways and their implications in disease development.By targeting PGAM1, researchers can gain insights into the role of glycolysis in cancer metabolism, metabolic diseases, and other health conditions. The PGAM1 Rabbit Monoclonal Antibody (CAB4170) provides a reliable tool for investigating the function and regulation of PGAM1, ultimately furthering our understanding of cellular metabolism and disease pathology.
Product Name:
PGAM1 Rabbit Monoclonal Antibody
SKU:
CAB4170
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PGAM1 (P18669).
cytoplasm, cytosol, extracellular exosome, extracellular region
Calculated MW:
29kDa
Observed MW:
28kDa
The protein encoded by this gene is a mutase that catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5223
Clone Number:
ARC0913
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PGAM1 Rabbit mAb (CAB4170) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
