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PGAM1 Monoclonal Antibody [PAT1G4AT] (CPAB0199)

SKU:
CPAB0199
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT1G4AT
Applications:
WB
ELISA
FC
€149
Frequently bought together:

Description

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PGAM1 Monoclonal Antibody [PAT1G4AT] (CPAB0199)

The PGAM1 Polyclonal Antibody (CPAB0199) is a valuable tool for researchers studying PGAM1, a key enzyme involved in glycolysis and cellular energy production. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the PGAM1 protein, this antibody enables accurate detection and analysis in various cell types, making it suitable for investigations in metabolism, cancer research, and metabolic disorders.

PGAM1, also known as phosphoglycerate mutase 1, plays a crucial role in the glycolytic pathway by catalyzing the conversion of 3-phosphoglycerate to 2-phosphoglycerate. Dysregulation of PGAM1 has been associated with various diseases, including cancer and metabolic disorders, making it a potential therapeutic target. Understanding the function and regulation of PGAM1 is essential for developing targeted treatments and interventions for these conditions.

Product Name:PGAM1 Antibody
Product Sku:CPAB0199
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PGAM1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PGAM1 amino acids 1-254 purified from Ecoli.
Clone:PAT1G4AT.
Reactivity:Human
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:PGAM1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:PGAM1 is part of the phosphoglycerate mutase family. PGAM1 is an essential component of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism and catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. PGAM1 is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). PGAM1 mutations lead to muscle phosphoglycerate mutase deficiency, a.k.a. glycogen storage disease X.
Synonyms:Phosphoglycerate mutase isozyme B, PGAM-B, PGAMA.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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