The PGA3 Polyclonal Antibody (CAB17321) is a crucial tool for research involving PGA3, a protein involved in immune regulation and inflammation modulation. Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in Western blot applications. By binding specifically to PGA3, this antibody enables accurate detection and analysis of PGA3 in various cell types, making it an essential tool for studies in immunology and cancer research.PGA3, also known as a key player in immune response modulation, plays a crucial role in regulating inflammation and immune homeostasis. Its significance in immune function makes it a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Understanding the activity of PGA3 is essential for the development of therapies that can effectively modulate immune function in these disease contexts.Overall, the PGA3 Polyclonal Antibody (CAB17321) is a valuable tool for researchers looking to deepen their understanding of PGA3 and its role in immune regulation and disease pathology. Its specificity and reliability make it an indispensable resource for advancing research in the field of immunology and cancer biology.
Product Name:
PGA3 Rabbit Polyclonal Antibody
SKU:
CAB17321
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 63-180 of human PGA3 (NP_001073275.1).
This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.
Purification Method:
Affinity purification
Gene ID:
643834
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PGA3 Rabbit pAb (CAB17321) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
