PGA3 Rabbit Polyclonal Antibody (CAB17321)
- SKU:
- CAB17321
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PGA3 Rabbit Polyclonal Antibody |
SKU: | CAB17321 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 63-180 of human PGA3 (NP_001073275.1). |
Sequence: | VDEQ PLEN YLDM EYFG TIGI GTPA QDFT VVFD TGSS NLWV PSVY CSSL ACTN HNRF NPED SSTY QSTS ETVS ITYG TGSM TGIL GYDT VQVG GISD TNQI FGLS ETEP GSFL YYAP FD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PGA3 |
Positive Sample: | C6,U-251MG,U-87MG,SGC-7901,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.
Purification Method: | Affinity purification |
Gene ID: | 643834 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |