The CD300A Polyclonal Antibody (PAC061886) is a valuable tool for researchers studying CD300A, an immune inhibitory receptor involved in immune regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for Western blot applications. By binding specifically to the CD300A protein, this antibody enables accurate detection and analysis in various cell types. Its use is particularly beneficial for investigations in immunology and cancer research.CD300A plays a pivotal role in maintaining immune homeostasis by controlling inflammation and suppressing allergic reactions.
Its involvement in immune response modulation has sparked interest in its potential as a therapeutic target for diseases such as cancer, autoimmune disorders, and chronic inflammation. By deepening our understanding of CD300A activity, researchers can pave the way for the development of novel therapies that modulate immune function in the context of these conditions.
Antibody Name:
PG_1424 Antibody (PACO61886)
Antibody SKU:
PACO61886
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Porphyromonas gingivalis
Immunogen:
Recombinant Porphyromonas gingivalis Peptidylarginine deiminase protein (44-556AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: PG_1424 antibody at 3.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 63 kDa. Observed band size: 63 kDa.
Background:
Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acid, c cleaning cycles in the mouth.
Synonyms:
Peptidylarginine deiminase (EC 3.5.3)
UniProt Protein Function:
Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth.