The PFN2 Polyclonal Antibody (CAB10007) is a valuable tool for researchers studying PFN2, a key protein involved in cytoskeletal dynamics and cell motility. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to PFN2, researchers can accurately detect and analyze the protein in a variety of cell types, making it an essential reagent for studies in cell biology, cancer research, and neuroscience.PFN2, also known as profilin-2, plays a crucial role in regulating actin polymerization and cell migration, making it a significant protein in processes such as cell division and tissue remodeling.
Dysregulation of PFN2 has been implicated in various diseases, including cancers and neurodegenerative disorders, highlighting the importance of understanding its function. The PFN2 Polyclonal Antibody provides a reliable tool for investigating the role of PFN2 in these disease contexts and for developing potential therapeutic interventions targeting this protein.
Product Name:
PFN2 Polyclonal Antibody
SKU:
CAB21539
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant Protein corresponding to a sequence within amino acids 1-140 of human PFN2 (NP_444252.1).
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.
Purification Method:
Affinity purification
Gene ID:
5217
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PFN2 Rabbit pAb (CAB21539) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
