The PFKP Polyclonal Antibody is a vital tool for researchers studying the phosphofructokinase platelet (PFKP) protein, an enzyme involved in the glycolysis pathway. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human samples, making it well-suited for use in Western blotting and other molecular applications.PFKP is crucial for energy production in cells and plays a key role in cancer metabolism, making it a promising target for cancer research. By utilizing the PFKP Polyclonal Antibody, researchers can accurately detect and analyze PFKP expression in various cell types, aiding in the study of metabolic pathways and potentially identifying new therapeutic targets for cancer treatment.
With its ability to specifically bind to the PFKP protein, this antibody is a valuable tool for investigating the role of glycolysis in cancer progression and developing targeted therapies aimed at disrupting metabolic pathways in cancer cells. Researchers interested in studying PFKP and its implications in cancer biology will find the PFKP Polyclonal Antibody to be an essential component of their research arsenal.
Product Name:
PFKP Polyclonal Antibody
SKU:
CAB21538
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 605-784 of human PFKP (NP_002618.1).
This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5214
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PFKP Rabbit pAb (CAB21538) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
