The PFKM Rabbit Monoclonal Antibody (CAB3671) is a powerful tool for researchers studying PFKM, a key enzyme in glycolysis that plays a crucial role in energy production and metabolism. This antibody, developed using rabbit monoclonal technology, is highly specific and sensitive for detecting PFKM in human samples, making it ideal for Western blotting and immunohistochemistry applications.PFKM is essential for the breakdown of glucose and the production of ATP, the energy currency of cells. Dysregulation of PFKM has been linked to various metabolic disorders, including cancer and diabetes. By targeting PFKM with this monoclonal antibody, researchers can gain insights into the role of this enzyme in disease progression and potentially identify novel therapeutic targets for intervention.
With its high specificity and sensitivity, the PFKM Rabbit Monoclonal Antibody (CAB3671) is a valuable tool for scientific investigations in the fields of metabolism, cancer biology, and drug development. Its ability to detect PFKM in various cell types and tissue samples makes it an essential resource for researchers striving to unravel the complexities of glycolysis and its implications for human health.
Product Name:
PFKM Rabbit Monoclonal Antibody
SKU:
CAB3671
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Fructose 6 Phosphate Kinase (P08237).
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
5213
Clone Number:
ARC0819
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PFKM Rabbit mAb (CAB3671) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
