PFKM Rabbit Polyclonal Antibody (CAB5477)
- SKU:
- CAB5477
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PFKM Rabbit Polyclonal Antibody |
SKU: | CAB5477 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 501-780 of human PFKM (NP_001160160.1). |
Sequence: | AYTG GLEL MEGR KQFD ELCI PFVV IPAT VSNN VPGS DFSV GADT ALNT ICTT CDRI KQSA AGTK RRVF IIET MGGY CGYL ATMA GLAA GADA AYIF EEPF TIRD LQAN VEHL VQKM KTTV KRGL VLRN EKCN ENYT TDFI FNLY SEEG KGIF DSRK NVLG HMQQ GGSP TPFD RNFA TKMG AKAM NWMS GKIK ESYR NGRI FANT PDSG CVLG MRKR ALVF QPVA ELKD QTDF EHRI PKEQ WWLK LRPI LKIL AKYE IDLD TSDH AHLE HITR KRSG EAAV |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | GSD7; PFK1; PFKA; PFKX; PFK-1; PFK-A; ATP-PFK; PPP1R122; PFKM |
Positive Sample: | HeLa,PC-3,RD,Mouse skeletal muscle,Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 85kDa |
Observed MW: | 85kDa |
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Purification Method: | Affinity purification |
Gene ID: | 5213 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |