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PFKM Monoclonal Antibody [PAT2F11A] (CPAB0174)

SKU:
CPAB0174
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT2F11A
Applications:
WB
ELISA
€149
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Description

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PFKM Monoclonal Antibody [PAT2F11A] (CPAB0174)

The PFKM Antibody (CPAB0174) is a polyclonal antibody designed for research involving PFKM, a key enzyme in glycolysis that is essential for cellular energy metabolism. Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in Western blot and immunohistochemistry applications. It specifically binds to the PFKM protein, allowing for accurate detection and analysis in various cell types.PFKM, also known as Phosphofructokinase muscle type, plays a crucial role in the regulation of glycolysis and ATP production in cells.

Dysregulation of PFKM has been implicated in various metabolic disorders and cancer progression, making it a valuable target for research in molecular biology and oncology. Understanding the role of PFKM in cellular metabolism is essential for uncovering potential therapeutic strategies for metabolic diseases and cancer treatment.

Product Name:PFKM Antibody
Product Sku:CPAB0174
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PFKM mAb, clone PAT2F11A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PFKM protein. .
Clone:PAT2F11A.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:PFKM antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2a
Background:PFKM is a regulatory glycolytic enzyme that converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. Mutations in PFKM gene have been related with glycogen storage disease type VII, also identified as Tarui disease.
Synonyms:EC 2.7.1.11, GSD7, PFK-1, PFK1, PFKA, PFKX, Phosphofructokinase-M, Phosphofructokinase 1, Phosphohexokinase, Phosphofructo-1-kinase isozyme A, MGC8699, PFKM.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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