The PFDN1 Polyclonal Antibody (CAB8681) is a valuable tool for researchers studying PFDN1, a protein involved in protein folding and cellular maintenance. This rabbit-derived antibody is highly specific to human PFDN1 samples and has been validated for use in Western blot applications.PFDN1, also known as prefoldin subunit 1, is essential for assisting in the folding of newly synthesized proteins and preventing protein aggregation. Dysregulation of PFDN1 has been linked to various diseases, making it a potential target for therapeutic interventions.By binding specifically to PFDN1, this polyclonal antibody enables researchers to detect and analyze the protein in different cell types, facilitating studies in molecular biology, cell biology, and disease mechanisms.
Understanding the role of PFDN1 in cellular processes is crucial for developing targeted therapies for diseases associated with protein misfolding and aggregation.Overall, the PFDN1 Polyclonal Antibody (CAB8681) is a reliable tool for investigating the function and regulation of PFDN1, offering valuable insights into the mechanisms underlying cellular protein quality control.
Product Name:
PFDN1 Rabbit Polyclonal Antibody
SKU:
CAB8681
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-122 of human PFDN1 (NP_002613.2).
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.
Purification Method:
Affinity purification
Gene ID:
5201
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PFDN1 Rabbit pAb (CAB8681) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
