PEX19 Rabbit Monoclonal Antibody (CAB19237)
- SKU:
- CAB19237
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PEX19
- D1S2223E
- HK33
- PBD12A
- PMP1
- PMPI
- PXF
- PXMP1
- peroxisomal biogenesis factor 19
Description
Product Name: | PEX19 Rabbit Monoclonal Antibody |
SKU: | CAB19237 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PEX19 (P40855). |
Sequence: | MAAA EEGC SVGA EADR ELEE LLES ALDD FDKA KPSP APPS TTTA PDAS GPQK RSPG DTAK DALF ASQE KFFQ ELFD SELA SQAT AEFE KAMK ELAE EEPH |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | PXF; HK33; PMP1; PMPI; PXMP1; PBD12A; D1S2223E; PEX19 |
Positive Sample: | HeLa,K-562 |
Conjugate: | Unmodified |
Cellular Localization: | Cytoplasm, Cytoplasmic side, Lipid-anchor, Peroxisome membrane. |
Calculated MW: | 33kDa |
Observed MW: | 35kDa |
This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 5824 |
Clone Number: | ARC2395 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |