PEX12 Rabbit Polyclonal Antibody (CAB16062)
- SKU:
- CAB16062
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | PEX12 Rabbit Polyclonal Antibody |
SKU: | CAB16062 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 290-359 of human PEX12 (NP_000277.1). |
Sequence: | YNSD SPLL PKMK TVCP LCRK TRVN DTVL ATSG YVFC YRCV FHYV RSHQ ACPI TGYP TEVQ HLIK LYSP EN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PAF-3; PBD3A; PEX12 |
Positive Sample: | U-87MG,MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Multi-pass membrane protein, Peroxisome membrane |
Calculated MW: | 41kDa |
Observed MW: | 41kDa |
This gene belongs to the peroxin-12 family. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS).
Purification Method: | Affinity purification |
Gene ID: | 5193 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |