The PEX11A Polyclonal Antibody (CAB17576) is a valuable tool for researchers studying Peroxisomal Biogenesis Factor 11 Alpha (PEX11A), a protein involved in peroxisome biogenesis and fission. Raised in rabbits, this antibody exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to PEX11A, this antibody allows for the detection and analysis of this important protein in various cell types, making it ideal for studies focusing on peroxisome biology and related diseases.
PEX11A plays a crucial role in the regulation of peroxisome dynamics, including membrane elongation and division. Dysregulation of PEX11A has been implicated in various peroxisome-related disorders, such as Zellweger syndrome and other peroxisomal biogenesis disorders. Understanding the function and regulation of PEX11A is essential for advancing our knowledge of peroxisome biology and developing potential therapies for peroxisome-related diseases.
Product Name:
PEX11A Rabbit Polyclonal Antibody
SKU:
CAB17576
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 110-180 of human PEX11A (NP_003838.1).
This gene is a member of the PEX11 family, which is composed of membrane elongation factors involved in regulation of peroxisome maintenance and proliferation. This gene product interacts with peroxisomal membrane protein 19 and may respond to outside stimuli to increase peroxisome abundance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
8800
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PEX11A Rabbit pAb (CAB17576) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
