The PEX10 Polyclonal Antibody (CAB16949) is a valuable tool for researchers studying the peroxisomal biogenesis factor 10 (PEX10) protein, which is essential for peroxisome assembly and function. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PEX10 protein, this antibody facilitates the detection and analysis of PEX10 in various cell types, making it an excellent choice for studies in cell biology and metabolism research.
PEX10 is a critical component of the peroxisomal biogenesis pathway, where it is involved in importing proteins into peroxisomes and maintaining their structure and function. Dysfunction of PEX10 has been linked to various peroxisomal disorders, highlighting the importance of studying this protein for understanding peroxisome-related diseases. By investigating the role of PEX10 in peroxisome biogenesis and function, researchers can gain insights into potential therapeutic targets for treating peroxisomal disorders and related conditions.
Product Name:
PEX10 Rabbit Polyclonal Antibody
SKU:
CAB16949
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 10-160 of human PEX10 (NP_002608.1).
This gene encodes a protein involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane. Mutations in this gene result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders, ranging from neonatal adrenoleukodystrophy to Zellweger syndrome. Alternative splicing results in two transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
5192
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of U-87MG, using PEX10 antibody (CAB16949) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
