PES1 Rabbit Polyclonal Antibody (CAB14506)
- SKU:
- CAB14506
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PES1 Rabbit Polyclonal Antibody |
SKU: | CAB14506 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PES1 (NP_055118.1). |
Sequence: | MGGL EKKK YERG SATN YITR NKAR KKLQ LSLA DFRR LCIL KGIY PHEP KHKK KVNK GSTA ARTF YLIK DIRF LLHE PIVN KFRE YKVF VRKL RKAY GKSE WNTV ERLK DNKP NYKL DHII KERY PTFI DALR DLDD ALSM CFLF STFP RT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PES; NOP7; PES1 |
Positive Sample: | MCF7,HepG2,Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus, nucleolus, nucleoplasm. |
Calculated MW: | 68kDa |
Observed MW: | 68kDa |
This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9.
Purification Method: | Affinity purification |
Gene ID: | 23481 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |