The Peroxiredoxin-6 Polyclonal Antibody (CAB2031) is essential for research involving peroxiredoxin-6, a key enzyme involved in antioxidant defense. This antibody, produced in rabbits, is highly sensitive and specific for detecting peroxiredoxin-6 in human samples, making it a valuable tool for Western blot applications. By targeting the peroxiredoxin-6 protein, researchers can analyze its expression in various cell types, providing insights into its role in oxidative stress response and potential implications in disease pathogenesis.Peroxiredoxin-6 is a critical player in maintaining cellular redox balance and protecting cells from oxidative damage.
Its dysregulation has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Studying the function of peroxiredoxin-6 with this antibody can help uncover novel therapeutic targets for these conditions and enhance our understanding of the mechanisms underlying oxidative stress-related pathologies. The Peroxiredoxin-6 Polyclonal Antibody is a valuable tool for researchers investigating the role of peroxiredoxin-6 in health and disease.
Product Name:
Peroxiredoxin 6 Rabbit Polyclonal Antibody
SKU:
CAB2031
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human Peroxiredoxin 6 (NP_004896.1).
The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
Purification Method:
Affinity purification
Gene ID:
9588
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Peroxiredoxin 6 antibody (CAB2031) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
