The Peroxiredoxin-5 Rabbit Monoclonal Antibody (CAB3954) is a cutting-edge research tool designed for scientists studying Peroxiredoxin-5, a vital antioxidant enzyme involved in redox regulation and cellular protection. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity towards Peroxiredoxin-5 in a variety of experimental settings.Peroxiredoxin-5, also known as PRDX5, is a key player in the defense against oxidative stress and the maintenance of cellular homeostasis. Its dysregulation has been linked to various human diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions. By targeting PRDX5, researchers can gain insights into its functions and potential therapeutic implications.
This antibody is validated for use in Western blotting, immunofluorescence, and immunohistochemistry applications, enabling precise detection and localization of Peroxiredoxin-5 in different cell types and tissues. Its reliability and reproducibility make it an essential tool for investigating the role of PRDX5 in oxidative stress, aging, and disease pathogenesis.In summary, the Peroxiredoxin-5 Rabbit Monoclonal Antibody (CAB3954) offers researchers a powerful means to explore the biology of Peroxiredoxin-5 and its implications for health and disease. Its superior performance and versatility make it a valuable asset in studies related to redox signaling
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein interacts with peroxisome receptor 1 and plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites is thought to result in transcript variants that use different in-frame translational start codons to generate isoforms that are targeted to the mitochondrion (isoform L) or peroxisome/cytoplasm (isoform S). Multiple related pseudogenes have been defined for this gene.
Purification Method:
Affinity purification
Gene ID:
25824
Clone Number:
ARC0873
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Peroxiredoxin 5 (PRDX5) (PRDX5) Rabbit mAb (CAB3954) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10148 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
